Our goal of this study is to prevent marijuana smoking in the human population. In this manuscript, an updated mathematical model was established by incorporating two additional compartments: The hospitalized class and the prisoner�s class. The updated model was validated, and it was shown to be novel compared to the non-user, experimental, recreational, and addicted (NERA) users� model. This distinction was crucial as it was challenging to prevent marijuana usage without these realistic classes. The entire population was split into six primary groups, including these new classes: non-users, experimental, recreational, addicted, hospitalized, and prisoners� class. Additionally, control techniques for marijuana prevention in the population were addressed with the aid of sensitivity analysis. The important point at which we may have determined the preliminary transmission rate of marijuana smoking was the basic reproductive number �0. Utilizing MATLAB, the Runge-Kutta method of order four was employed for the numerical simulation of the updated model to investigate the impact of control measures on marijuana smoking prevention. © 2024 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)