Modeling and theoretical description of gas transport through mixed matrix membranes synthesized by including a covalent organic framework are essential for the efficient design of these membranes. This paper reports a theoretical analysis of various permeation models for gas transport through covalent organic framework-based mixed matrix membranes. The existing models, such as Bruggeman, Maxwell, and Lewis Nielson, were analyzed. The Maxwell model calculated the permeation through voids and filler by considering interfacial defects in the covalent organic framework mixed matrix membrane's structure. Hence, dual Maxwell model was used to estimate gas transport through mixed matrix membranes. The percentage absolute average relative error of the dual Maxwell model was found to be less than 4 . The results suggest that the dual Maxwell model effectively describes gas transport through a covalent organic framework mixed matrix membrane. © 2023 Wiley-VCH GmbH.