Promoted Bimetallic Cu/ZnO catalysts were synthesized on Al2O3, Al2O3-ZrO2 and zeolite supports. The catalytic performances in CO2 hydrogenation reaction were evaluated in a fixed-bed reactor system at H2:CO2 (3:1), 22.5 bar and 250 °C for 5 h. The catalyst supported on Al2O3�ZrO2 resulted in the highest CO2 conversion (15.81) and methanol selectivity (68.77). In general, all the tested catalysts show low selectivity towards ethanol. © 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.