Biogas is a source of clean energy that mainly consists of methane (CH4) and carbon dioxide (CO2). However, the presence of CO2 in biogas limits the heating value of the gas. Thus, biogas upgrading is a crucial process for reducing the CO2 content in raw biogas for purified biomethane production. Chemical absorption is a matured technology for CO2 removal process. The selection of chemical solvent with desirable characteristics is a substantial consideration for the effectiveness of the process. In this work, a potential solvent, 2-amino-2-methyl-1-propanol (AMP) was tested for the removal of CO2 from simulated biogas. The absorption process was conducted at different gas flow rates (22.1 kmol/m2.hr and 26.5 kmol/m2.hr) in a packed column at an operating pressure of 2 bars. The performance was evaluated in terms of percentage of CO2 removal along the column. It was found that the CO2 removal performance decreased by about 15 at higher gas flow rates. Besides, the absorption efficiency of AMP was also compared with a well-established solvent, monoethanolamine (MEA). The experiment substantiated that 30 wt. MEA effectively captured CO2 with 100 removal as compared to 30 wt. and 40 wt. AMP with only 69 and 87 removal. In order to achieve high reaction rate for efficient CO2 removal, the addition of activator to form a blended amine solution with AMP was suggested to accelerate the CO2 absorption performance. © 2021 Institute of Physics Publishing. All rights reserved.