Whenever T-junctions are used in chemical processes and petroleum industries for two-phase separation, a maldistribution of phases is observed between outlets of the junction. Currently, the regular T-junctions are utilized in the industry due to which equipment downstream faces high liquid carryovers. Unfortunately, downstream equipment is not capable of handling high liquid carryovers and they trip frequently, consequently. This review manuscript summarizes the effect of different factors that influence phase separation in the T-junction. This article refers to the geometrical parameters, phase superficial velocity flow regimes encounter during the separation process, and different side arm modifications. This article is a contribution to this field as it summarizes and concludes all these factors comprehensively, to give a verdict on ways to improve phase separation. It is also recommended that the effect of side arm modifications or combinations must be explored for further understanding. © 2021. All Rights Reserved.