A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application

Said, N. and Lau, W.J. and Ho, Y.-C. and Lim, S.K. and Zainol Abidin, M.N. and Ismail, A.F. (2021) A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application. Membranes, 11 (10). ISSN 20770375

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Abstract

Dialyzers have been commercially used for hemodialysis application since the 1950s, but progress in improving their efficiencies has never stopped over the decades. This article aims to provide an up-to-date review on the commercial developments and recent laboratory research of dialyzers for hemodialysis application and to discuss the technical aspects of dialyzer development, including hollow fiber membrane materials, dialyzer design, sterilization processes and flow sim-ulation. The technical challenges of dialyzers are also highlighted in this review, which discusses the research areas that need to be prioritized to further improve the properties of dialyzers, such as flux, biocompatibility, flow distribution and urea clearance rate. We hope this review article can provide insights to researchers in developing/designing an ideal dialyzer that can bring the best hemodialysis treatment outcomes to kidney disease patients. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Item Type: Article
Additional Information: cited By 22
Uncontrolled Keywords: Biocompatibility; Design; Hemodialyzers; Patient treatment; Urea, Blood; Commercial development; Commercial dialyzer; Dialyzer design; Haemodialysis; Hollow-fibre membrane; Membrane material; Sterilization process; Technical aspects; Technical challenges, Dialysis
Depositing User: Mr Ahmad Suhairi UTP
Date Deposited: 10 Nov 2023 03:28
Last Modified: 10 Nov 2023 03:28
URI: https://khub.utp.edu.my/scholars/id/eprint/14386

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