The purpose of this research is to investigate wastewater treatment with ozone pre-treatment and post-treatment integrated with Moving Bed Biofilm Reactor (MBBR). Ozonation as a pre-treatment served to increase the Biochemical Oxygen Demand (BOD)/Chemical Oxygen Demand (COD) ratio while as a post-treatment to remove the remaining organic residues. Ozone doses were 1 mg/min, 4 mg/min, 20 mg/min, and 40 mg/min. In the pre-treatment, ozone produced a BOD/COD value of 0.68. The MBBR process had a COD and color removal efficiency of 68.89 and 67, respectively. In the MBBR process without ozone pre-treatment, the efficiency of COD and color removal were 79.31 and 64.7, respectively. The effluent treatment results from MBBR were then processed with ozone and showed the highest COD and color removal results of 76.8 and 99, respectively. In this study, the processing with ozone as post-treatment was better than the pre-treatment. © 2021