Singh D., Ph.D. and Narayanan S., Ph.D. and Müller C.P., Ph.D. and Vicknasingam B., Ph.D. and Yücel M., Ph.D. and Ho E.T.W., Ph.D. and Hassan Z., Ph.D. and Mansor S.M., Ph.D. (2019) Long-Term Cognitive Effects of Kratom (Mitragyna speciosa Korth.) Use. Journal of Psychoactive Drugs, 51 (1). pp. 19-27. ISSN 02791072
Full text not available from this repository.Abstract
Kratom or Mitragyna speciosa (Korth.) is a medicinal plant of Southeast Asia. As a result of its opioid-like effects, it remains unknown whether consumption of kratom tea is associated with impaired cognitive function. We assessed the cognitive function of 70 regular kratom users and 25 control participants using the Cambridge Neuropsychological Test Automated Battery. Participants performed six neuropsychological tasks that assessed motor, learning and memory, attention and executive function. Relative to control participants, higher consumption (>3 glasses daily or mitragynine doses between 72.5 mg and 74.9 mg) of kratom tea was selectively associated with impaired performance on the Paired Associates Learning task, reflecting deficits in visual episodic memory and new learning. Overall, the performance of kratom users compared to control participants, and the performance of high (>3 glasses per day) as well as low (�3 glasses per day) kratom using groups, were comparable on all neuropsychological domains. Higher intake of kratom juice (>3 glasses daily) did not appear to impair motor, memory, attention or executive function of regular kratom users. © 2018, © 2018 Taylor & Francis Group, LLC.
Item Type: | Article |
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Additional Information: | cited By 29 |
Uncontrolled Keywords: | kratom extract; mitragynine; plant extract; unclassified drug; narcotic analgesic agent; plant extract, adult; Article; cognition; cognition assessment; cognitive defect; cognitive function test; controlled study; cross-sectional study; delayed matching to position test; drug use; episodic memory; female; human; learning; learning and memory test; male; mass fragmentography; medicinal plant; Mitragyna; Mitragyna speciosa; motor function test; neuropsychological test; psychologist; spatial memory test; structured questionnaire; tea; visual discrimination learning test; young adult; adverse event; attention; cognition; drug effect; memory; Mitragyna; psychology; withdrawal syndrome, Adult; Analgesics, Opioid; Attention; Cognition; Cross-Sectional Studies; Female; Humans; Learning; Male; Memory; Mitragyna; Plant Extracts; Plants, Medicinal; Substance Withdrawal Syndrome |
Depositing User: | Mr Ahmad Suhairi UTP |
Date Deposited: | 10 Nov 2023 03:26 |
Last Modified: | 10 Nov 2023 03:26 |
URI: | https://khub.utp.edu.my/scholars/id/eprint/12262 |