Dimensions
DimensionsChowdhury, M.R. and Moshikur, R.M. and Wakabayashi, R. and Tahara, Y. and Kamiya, N. and Moniruzzaman, M. and Goto, M. (2019) Development of a novel ionic liquid-curcumin complex to enhance its solubility, stability, and activity. Chemical Communications, 55 (54). pp. 7737-7740. ISSN 13597345
Full text not available from this repository.Abstract
We report a one-step emulsification and rapid freeze-drying process to develop a curcumin-ionic liquid (CCM-IL) complex that could be readily dispersed in water with a significantly enhanced solubility of �8 mg mL-1 and half-life (t1/2) of �260 min compared with free CCM (solubility �30 nM and t1/2 � 20 min). This process using an IL consisting of a long chain carbon backbone as a surfactant, may provide an alternative way of enhancing the solubility of poorly water-soluble drugs. © 2019 The Royal Society of Chemistry.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 42 |
| Uncontrolled Keywords: | carbon; curcumin; ionic liquid; water, Article; chemical structure; concentration (parameter); controlled study; drug solubility; emulsion; freeze drying; process development; solubility |
| Depositing User: | Mr Ahmad Suhairi UTP |
| Date Deposited: | 10 Nov 2023 03:26 |
| Last Modified: | 10 Nov 2023 03:26 |
| URI: | https://khub.utp.edu.my/scholars/id/eprint/12124 |
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