For some applications of implantable polymeric devices, material degradation and disappearance with time is necessary. In such a case, control in the polymer applications can be achieved through understanding the process of degradation. Heat effect on physical changes of polymeric materials under service condition should also not be overlooked. Poly octanediol citrate/Nano silica composite was developed and tested for glass transition (Tg) and physical degradation within the environmental factors that impact the use of the Poly octanediol citrate/Nano silica composite for medical application. Degradation correlated well with the nano silica content while the indicated low Tg value confirmed the amorphousness of the Poly octanediol citrate/Nano silica composite at 37°C. © 2019 Elsevier Ltd. All rights reserved.