From a regression analysis perspective, this paper focused on literature about TiO2 nano particles. The particles on focus entailed those that had been suspended in ethylene glycol and water-at a ratio of 60:40. Indeed, regression analysis has gained application in contexts such as the turbulent Reynolds number, especially with the aim of establishing the impact of the ratio of the base fluid on heat transfer coefficients, as well as the target materials' thermal properties. From the findings, this study infers that when the water-ethylene glycol mixture is used at a ratio of 60:40, the rate of heat transfer is higher than that which is obtained when water is used solely. Additional findings established from the examination of the impact of material concentration and temperature on the rate of nanofluids' heat transfer suggested that as temperature increases, the rate of heat transfer decreases. However, it was noted that an increase in concentration exhibits a positive correlation with the nanofluids' rate of heat transfer whereby an increase in the former parameter (concentration) leads to an increase in the latter (rate of nanofluids heat transfer). © 2019 Materials and Energy Research Center. All rights reserved.