In advanced control, a control target tracks the set points and tends to achieve optimal operation of a process. Model predictive control (MPC) is used to track the set points. When the set points correspond to an optimum economic trajectory that is sent from an economic layer, the process will be gradually reaching the optimal operation. This study proposes the integration of an economic layer and MPC layer to solve the problem of different time scale and unreachable set points. Both layers require dynamic models that are subject to objective functions. The prediction output of a model is not always asymptotically equal to the measured output of a process. Therefore, Kalman filter is proposed as a state feedback to the two-layer integration. The proposed controller only considers the linear empirical model and the inherent model is identified by system identification, which is assumed to be an ample representation of the process. A depropanizer process case study has been used for demonstration of the proposed technique. The result shows that the proposed controller tends to improve the profit of the process smoothly and continuously, until the process reaches an asymptotically maximum profit point. © 2018 Institute of Automatic Control - Silesian University of Technology. All rights reserved.