The impact of phenotypic heterogeneity of tumour cells on treatment and relapse dynamics.

by Michael Raatz, Saumil Shah, Guranda Chitadze, Monika Brüggemann, Arne Traulsen
Published 2021-02-01

The Serine Protease CD26/DPP4 in Non-Transformed and Malignant T Cells

by Guranda Chitadze, Ulrike Wehkamp, Ottmar Janssen, Monika Brüggemann, Marcus Lettau
Published 2021-11-01

Immune Gene Rearrangements: Unique Signatures for Tracing Physiological Lymphocytes and Leukemic Cells

by Michaela Kotrova, Nikos Darzentas, Christiane Pott, Claudia D. Baldus, Monika Brüggemann
Published 2021-06-01

Insights into IGH clonal evolution in BCP-ALL: frequency, mechanisms, associations, and diagnostic implications

by Franziska Darzentas, Monika Szczepanowski, Michaela Kotrová, Alina Hartmann, Alina Hartmann, Alina Hartmann, Thomas Beder, Thomas Beder, Nicola Gökbuget, Stefan Schwartz, Stefan Schwartz, Lorenz Bastian, Lorenz Bastian, Lorenz Bastian, Claudia Dorothea Baldus, Claudia Dorothea Baldus, Claudia Dorothea Baldus, Karol Pál, Nikos Darzentas, Monika Brüggemann, Monika Brüggemann, Monika Brüggemann
Published 2023-04-01

A systematic literature review and meta-analysis of minimal residual disease as a prognostic indicator in adult B-cell acute lymphoblastic leukemia

by Renato Bassan, Monika Brüggemann, Hoi-Shen Radcliffe, Elizabeth Hartfield, Georg Kreuzbauer, Sally Wetten
Published 2019-10-01

High-Throughput, Amplicon-Based Sequencing of the CREBBP Gene as a Tool to Develop a Universal Platform-Independent Assay.

by Marc W Fuellgrabe, Dietrich Herrmann, Henrik Knecht, Sven Kuenzel, Michael Kneba, Christiane Pott, Monika Brüggemann
Published 2015-01-01

CD56 expression in T-cell acute lymphoblastic leukemia is associated with non-thymic phenotype and resistance to induction therapy but no inferior survival after risk-adapted thera...

by Lars Fischer, Nicola Gökbuget, Stefan Schwartz, Thomas Burmeister, Harald Rieder, Monika Brüggemann, Dieter Hoelzer, Eckhard Thiel
Published 2009-02-01

Frequent, high density expression of surface CD38 as a potential therapeutic target in adult T-lineage acute lymphoblastic leukemia

by Sebastian Koslowski, Rainer Glauben, Stefan Habringer, Thomas Burmeister, Ulrich Keller, Monika Brüggemann, Nicola Gökbuget, Stefan Schwartz
Published 2023-09-01

Impact of Blinatumomab Treatment on Bone Marrow Function in Patients with Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

by Hagop M. Kantarjian, Gerhard Zugmaier, Monika Brüggemann, Brent L. Wood, Heinz A. Horst, Yi Zeng, Giovanni Martinelli
Published 2021-11-01

Testing for minimal residual disease in adults with acute lymphoblastic leukemia in Europe: a clinician survey

by Arnaud Pigneux, Pau Montesinos, Ze Cong, Xinke Zhang, Anja K. Pownell, Heather Wieffer, Jan McKendrick, Monika Brüggemann
Published 2018-11-01

Comprehensive translocation and clonality detection in lymphoproliferative disorders by next-generation sequencing

by Dörte Wren, Brian A. Walker, Monika Brüggemann, Mark A. Catherwood, Christiane Pott, Kostas Stamatopoulos, Anton W. Langerak, David Gonzalez
Published 2017-02-01

Blinatumomab as first salvage versus second or later salvage in adults with relapsed/refractory B‐cell precursor acute lymphoblastic leukemia: Results of a pooled analysis

by Max S. Topp, Anthony S. Stein, Nicola Gökbuget, Heinz‐August Horst, Nicolas Boissel, Giovanni Martinelli, Hagop Kantarjian, Monika Brüggemann, Yuqi Chen, Gerhard Zugmaier
Published 2021-04-01

The New EU Regulation on In Vitro Diagnostic Medical Devices: Implications and Preparatory Actions for Diagnostic Laboratories

by Bart R. Lubbers, Anke Schilhabel, Christa M. Cobbaert, David Gonzalez, Isabel Dombrink, Monika Brüggemann, W. Marieke Bitter, Jacques J.M. van Dongen
Published 2021-05-01

Loss-of-function but not dominant-negative intragenic IKZF1 deletions are associated with an adverse prognosis in adult BCR-ABL-negative acute lymphoblastic leukemia

by Benjamin Kobitzsch, Nicola Gökbuget, Stefan Schwartz, Richard Reinhardt, Monika Brüggemann, Andreas Viardot, Ralph Wäsch, Michael Starck, Eckhard Thiel, Dieter Hoelzer, Thomas Burmeister
Published 2017-10-01

Combining Cellular Immunization and Phage Display Screening Results in Novel, FcγRI-Specific Antibodies

by Steffen Krohn, Tosca Holtrop, Arianne M. Brandsma, Petra Moerer, Maaike Nederend, Nikos Darzentas, Monika Brüggemann, Katja Klausz, Jeanette H. W. Leusen, Matthias Peipp
Published 2024-04-01

Dominant T-cell Receptor Delta Rearrangements in B-cell Precursor Acute Lymphoblastic Leukemia: Leukemic Markers or Physiological γδ T Repertoire?

by Miriam Kelm, Franziska Darzentas, Nikos Darzentas, Michaela Kotrova, Wiebke Wessels, Sonja Bendig, Claudia D. Baldus, Marcus Lettau, Nicola Gökbuget, Dieter Kabelitz, Monika Brüggemann, Guranda Chitadze
Published 2023-09-01

P762: HEMATOPOIETIC PROGENITOR CELL-REACTIVE T CELL CLONES CAN RECOGNIZE VIRAL EPITOPES IN APLASTIC ANEMIA BONE MARROW

by Amin Ben Hamza, Carlotta Welters, Monika Brüggemann, Kerstin Dietze, Lars Bullinger, Tim H Brümmendorf, Thomas Winkler, Julian Strobel, Holger Hackstein, Klaus Dornmair, Fabian Beier, Leo Hansmann
Published 2023-08-01

Critical Implications of IVDR for Innovation in Diagnostics: Input From the BioMed Alliance Diagnostics Task Force

by Isabel Dombrink, Bart R. Lubbers, Loredana Simulescu, Robin Doeswijk, Olga Tkachenko, Elisabeth Dequeker, Alan G. Fraser, Jacques J. M. van Dongen, Christa Cobbaert, Monika Brüggemann, Elizabeth Macintyre
Published 2022-06-01

IGH Rearrangement Evolution in Adult KMT2A-rearranged B-cell Precursor ALL: Implications for Cell-of-origin and MRD Monitoring

by Franziska Darzentas, Monika Szczepanowski, Michaela Kotrová, Miriam Kelm, Alina Hartmann, Thomas Beder, Nicola Gökbuget, Martin Neumann, Lorenz Bastian, Claudia D. Baldus, Karol Pál, Nikos Darzentas, Monika Brüggemann
Published 2023-01-01

A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia

by Fabian Lang, Lydia Wunderle, Susanne Badura, Eberhard Schleyer, Monika Brüggemann, Hubert Serve, Susanne Schnittger, Nicola Gökbuget, Heike Pfeifer, Sebastian Wagner, Kevin Ashelford, Gesine Bug, Oliver G. Ottmann
Published 2020-09-01