Insulin resistance is a risk factor for diabetes but not cardiovascular disease in the elderly: results from long-term follow-up of the Prospective Study of Pravastatin in the Elde...

by Welsh, P., Preiss, D., Lloyd, S., Ford, I., Buckley, B.M., Jukema, J.W., Sattar, N.
Published 2014

Total cerebral blood flow and mortality in old age A 12-year follow-up study

by Sabayan, B., Grond, J. van der, Westendorp, R.G., Jukema, J.W., Ford, I., Buckley, B.M., Sattar, N., Osch, M.J.P. van, Buchem, M.A. van, Craen, A.J.M. de
Published 2013

Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies

by Trompet, S., Postmus, I., Slagboom, P.E., Heijmans, B.T., Smit, R.A.J., Maier, A.B., Buckley, B.M., Sattar, N., Stott, D.J., Ford, I., Westendorp, R.G.J., Craen, A.J.M. de, Jukema, J.W.
Published 2016

Long-Term Effects of Statin Treatment in Elderly People: Extended Follow-Up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)

by Lloyd, S.M., Stott, D.J., Craen, A.J.M. de, Kearney, P.M., Sattar, N., Perry, I., Packard, C.J., Briggs, A., Marchbank, L., Comber, H., Jukema, J.W., Westendorp, R.G.J., Trompet, S., Buckley, B.M., Ford, I.
Published 2013

Non-Homologous End-Joining Pathway Associated with Occurrence of Myocardial Infarction: Gene Set Analysis of Genome-Wide Association Study Data

by Verschuren, J.J.W., Trompet, S., Deelen, J., Stott, D.J., Sattar, N., Buckley, B.M., Ford, I., Heijmans, B.T., Guchelaar, H.J., Houwing-Duistermaat, J.J., Slagboom, P.E., Jukema, J.W.
Published 2013

Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER long-term follow-up

by Welsh, P., Preiss, D., Lloyd, S.M., Craen, A.J. de, Jukema, J.W., Westendorp, R.G., Buckley, B.M., Kearney, P.M., Briggs, A., Stott, D.J., Ford, I., Sattar, N.
Published 2014

Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly

by Akao, H., Polisecki, E., Kajinami, K., Trompet, S., Robertson, M., Ford, I., Jukema, J.W., Craen, A.J.M. de, Westendorp, R.G.J., Shepherd, J., Packard, C., Buckley, B.M., Schaefer, E.J.
Published 2012

Association of visit-to-visit variability in blood pressure with cognitive function in old age: prospective cohort study

by Sabayan, B., Wijsman, L.W., Foster-Dingley, J.C., Stott, D.J., Ford, I., Buckley, B.M., Sattar, N., Jukema, J.W., Osch, M.J.P. van, Grond, J. van der, Buchem, M.A. van, Westendorp, R.G.J., Craen, A.J.M. de, Mooijaart, S.P.
Published 2013

ABCA1 gene variation and heart disease risk reduction in the elderly during pravastatin treatment

by Akao, H., Polisecki, E., Schaefer, E.J., Trompet, S., Robertson, M., Ford, I., Jukema, J.W., Craen, A.J.M. de, Packard, C., Buckley, B.M., Kajinami, K., PROspective Study Pravastatin Elde
Published 2014

Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy

by Shiffman, D., Trompet, S., Louie, J.Z., Rowland, C.M., Catanese, J.J., Iakoubova, O.A., Kirchgessner, T.G., Westendorp, R.G.J., Craen, A.J.M. de, Slagboom, P.E., Buckley, B.M., Stott, D.J., Sattar, N., Devlin, J.J., Packard, C.J., Ford, I., Sacks, F.M., Jukema, J.W.
Published 2012

In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at ris...

by Postmus, I., Johnson, P.C.D., Trompet, S., Craen, A.J.M. de, Slagboom, P.E., Devlin, J.J., Shiffman, D., Sacks, F.M., Kearney, P.M., Stott, D.J., Buckley, B.M., Sattar, N., Ford, I., Westendorp, R.G.J., Jukema, J.W.
Published 2014

KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly

by Akao, H., Polisecki, E., Kajinami, K., Trompet, S., Robertson, M., Ford, I., Jukema, J.W., Craen, A.J.M. de, Westendorp, R.G.J., Shepherd, J., Packard, C., Buckley, B.M., Schaefer, E.J., Prospective Study Pravastatin
Published 2012

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium

by Bis, J.C., Sitlani, C., Irvin, R., Avery, C.L., Smith, A.V., Sun, F.G., Evans, D.S., Musani, S.K., Li, X.H., Trompet, S., Krijthe, B.P., Harris, T.B., Quibrera, P.M., Brody, J.A., Demissie, S., Davis, B.R., Wiggins, K.L., Tranah, G.J., Lange, L.A., Sotoodehnia, N., Stott, D.J., Franco, O.H., Launer, L.J., Sturmer, T., Taylor, K.D., Cupples, L.A., Eckfeldt, J.H., Smith, N.L., Liu, Y.M., Wilson, J.G., Heckbert, S.R., Buckley, B.M., Ikram, M.A., Boerwinkle, E., Chen, Y.D.I., Craen, A.J.M. de, Uitterlinden, A.G., Rotter, J.I., Ford, I., Hofman, A., Sattar, N., Slagboom, P.E., Westendorp, R.G.J., Gudnason, V., Vasan, R.S., Lumley, T., Cummings, S.R., Taylor, H.A., Post, W., Jukema, J.W., Stricker, B.H., Whitsel, E.A., Psaty, B.M., Arnett, D.
Published 2015

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure

by Smith, J.G., Felix, J.F., Morrison, A.C., Kalogeropoulos, A., Trompet, S., Wilk, J.B., Gidlof, O., Wang, X.C., Morley, M., Mendelson, M., Joehanes, R., Ligthart, S., Shan, X.Y., Bis, J.C., Wang, Y.A., Sjogren, M., Ngwa, J., Brandimarto, J., Stott, D.J., Aguilar, D., Rice, K.M., Sesso, H.D., Demissie, S., Buckley, B.M., Taylor, K.D., Ford, I., Yao, C., Liu, C.Y., Sotoodehnia, N., Harst, P. van der, Stricker, B.H.C., Kritchevsky, S.B., Liu, Y.M., Gaziano, J.M., Hofman, A., Moravec, C.S., Uitterlinden, A.G., Kellis, M., Meurs, J.B. van, Margulies, K.B., Dehghan, A., Levy, D., Olde, B., Psaty, B.M., Cupples, L.A., Jukema, J.W., Djousse, L., Franco, O.H., Boerwinkle, E., Boyer, L.A., Newton-Cheh, C., Butler, J., Vasan, R.S., Cappola, T.P., Smith, N.L., CHARGE-SCD Consortium, EchoGen Consortium, QT-IGC Consortium, CHARGE-QRS Consortium
Published 2016

White Matter Lesion Progression Genome-Wide Search for Genetic Influences

by Hofer, E., Cavalieri, M., Bis, J.C., DeCarli, C., Fornage, M., Sigurdsson, S., Srikanth, V., Trompet, S., Verhaaren, B.F.J., Wolf, C., Yang, Q., Adams, H.H.H., Amouyel, P., Beiser, A., Buckley, B.M., Callisaya, M., Chauhan, G., Craen, A.J.M. de, Dufouil, C., Duijn, C.M. van, Ford, I., Freudenberger, P., Gottesman, R.F., Gudnason, V., Heiss, G., Hofman, A., Lumley, T., Martinez, O., Mazoyer, B., Moran, C., Niessen, W.J., Phan, T., Psaty, B.M., Satizabal, C.L., Sattar, N., Schilling, S., Shibata, D.K., Slagboom, P.E., Smith, A., Stott, D.J., Taylor, K.D., Thomson, R., Toglhofer, A.M., Tzourio, C., Buchem, M. van, Wang, J., Westendorp, R.G.J., Windham, B.G., Vernooij, M.W., Zijdenbos, A., Beare, R., Debette, S., Ikram, M.A., Jukema, J.W., Launer, L.J., Longstreth, W.T., Mosley, T.H., Seshadri, S., Schmidt, H., Schmidt, R., Cohorts Heart Aging Res Genomic Ep
Published 2015

Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval

by Avery, C.L., Sitlani, C.M., Arking, D.E., Arnett, D.K., Bis, J.C., Boerwinkle, E., Buckley, B.M., Chen, Y.D.I., Craen, A.J.M. de, Eijgelsheim, M., Enquobahrie, D., Evans, D.S., Ford, I., Garcia, M.E., Gudnason, V., Harris, T.B., Heckbert, S.R., Hochner, H., Hofman, A., Hsueh, W.C., Isaacs, A., Jukema, J.W., Knekt, P., Kors, J.A., Krijthe, B.P., Kristiansson, K., Laaksonen, M., Liu, Y., Li, X., MacFarlane, P.W., Newton-Cheh, C., Nieminen, M.S., Oostra, B.A., Peloso, G.M., Porthan, K., Rice, K., Rivadeneira, F.F., Rotter, J.I., Salomaa, V., Sattar, N., Siscovick, D.S., Slagboom, P.E., Smith, A.V., Sotoodehnia, N., Stott, D.J., Stricker, B.H., Sturmer, T., Trompet, S., Uitterlinden, A.G., Duijn, C. van, Westendorp, R.G.J., Witteman, J.C., Whitsel, E.A., Psaty, B.M.
Published 2014

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

by Dehghan, A., Bis, J.C., White, C.C., Smith, A.V., Morrison, A.C., Cupples, L.A., Trompet, S., Chasman, D.I., Lumley, T., Volker, U., Buckley, B.M., Ding, J.Z., Jensen, M.K., Folsom, A.R., Kritchevsky, S.B., Girman, C.J., Ford, I., Dorr, M., Salomaa, V., Uitterlinden, A.G., Eiriksdottir, G., Vasan, R.S., Franceschini, N., Carty, C.L., Virtamo, J., Demissie, S., Amouyel, P., Arveiler, D., Heckbert, S.R., Ferrieres, J., Ducimetiere, P., Smith, N.L., Wang, Y.A., Siscovick, D.S., Rice, K.M., Wiklund, P.G., Taylor, K.D., Evans, A., Kee, F., Rotter, J.I., Karvanen, J., Kuulasmaa, K., Heiss, G., Kraft, P., Launer, L.J., Hofman, A., Markus, M.R.P., Rose, L.M., Silander, K., Wagner, P., Benjamin, E.J., Lohman, K., Stott, D.J., Rivadeneira, F., Harris, T.B., Levy, D., Liu, Y.M., Rimm, E.B., Jukema, J.W., Volzke, H., Ridker, P.M., Blankenberg, S., Franco, O.H., Gudnason, V., Psaty, B.M., Boerwinkle, E., O'Donnell, C.J.
Published 2016

PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population

by Postmus, I., Trompet, S., Craen, A.J.M. de, Buckley, B.M., Ford, I., Stott, D.J., Sattar, N., Slagboom, P.E., Westendorp, R.G.J., Jukema, J.W.
Published 2013

Pravastatin and cognitive function in the elderly. Results of the PROSPER study

by Trompet, S., Vliet, P. van, Craen, A.J.M. de, Jolles, J., Buckley, B.M., Murphy, M.B., Ford, I., Macfarlane, P.W., Sattar, N., Packard, C.J., Stott, D.J., Shepherd, J., Bollen, E.L.E.M., Blauw, G.J., Jukema, J.W., Westendorp, R.G.J.
Published 2010

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus

by Oei, L., Hsu, Y.H., Styrkarsdottir, U., Eussen, B.H., Klein, A. de, Peters, M.J., Halldorsson, B., Liu, C.T., Alonso, N., Kaptoge, S.K., Thorleifsson, G., Hallmans, G., Hocking, L.J., Husted, L.B., Jameson, K.A., Kruk, M., Lewis, J.R., Patel, M.S., Scollen, S., Svensson, O., Trompet, S., Schoor, N.M. van, Zhu, K., Buckley, B.M., Cooper, C., Ford, I., Goltzman, D., Gonzalez-Macias, J., Langdahl, B.L., Leslie, W.D., Lips, P., Lorenc, R.S., Olmos, J.M., Pettersson-Kymmer, U., Reid, D.M., Riancho, J.A., Slagboom, P.E., Garcia-Ibarbia, C., Ingvarsson, T., Johannsdottir, H., Luben, R., Medina-Gomez, C., Arp, P., Nandakumar, K., Palsson, S.T., Sigurdsson, G., Meurs, J.B.J. van, Zhou, Y.H., Hofman, A., Jukema, J.W., Pols, H.A.P., Prince, R.L., Cupples, L.A., Marshall, C.R., Pinto, D., Sato, D., Scherer, S.W., Reeve, J., Thorsteinsdottir, U., Karasik, D., Richards, J.B., Stefansson, K., Uitterlinden, A.G., Ralston, S.H., Ioannidis, J.P.A., Kiel, D.P., Rivadeneira, F., Estrada, K.
Published 2014